Hydrogen Bromide → 6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone

HRID 1608045Notes

Reaction equation

HRID 1608045 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[C:9](=[O:13])[CH2:8][CH2:7][CH2:6]2.Br>>[OH:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[C:9](=[O:13])[CH2:8][CH2:7][CH2:6]2

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 141126-Methoxy-alpha-tetralone

Product 1

HCID 46794946-Hydroxy-3,4-dihydro-1(2H)-naphthalenone

Procedure

2 mols cf 6-methoxy-1-tetralone are heated at 125° C. in 2 l of 48% strength aqueous hydrobromic acid for 3 hours. On cooling, the product precipitates and is filtered off with suction and dried. If necessary, it can be recrystallized from water.

Workup

  1. temperatureOn cooling
  2. customthe product precipitates
  3. filtrationis filtered off with suction
  4. customdried
  5. customIf necessary, it can be recrystallized from water

Sources & evidence

ORD record
ord-d9df1907fb1f436196784dcb6e16e69d
Source dataset
uspto-grants-1989_09
Patent number
US04868332

Reaction notes

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