HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 1,5-Dihydro-4,1-benzoxazepin-2(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | HCID 19836746 | HCID 19836746 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1,5-Dihydro-4,1-benzoxazepin-2(3H)-one | HCID 15887754 | — |
Reaction Steps
1 g o-amino-benzyloxy acetic acid and 1.1 g dicyclohexyl carbodiimide were stirred in 15 ml refluxing methanol for 8 hours. The mixture was evaporated, and the residue was stirred with 50 ml acetone and filtered, whereafter the filtrate was evaporated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04870073 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-70d73d4557524fdab50fb8ca6434fed6 |
| Source note | uspto-grants-1989_09 |