反应详情

A mixture of 3.00 gm (0.019 mole) of 2-quinolinecarboxaldehyde, 3.44 gm (0.019 mole) of m-nitrobenzhydrazide and 100 ml of ethanol is refluxed for 9 hrs. The hot solution is filtered and cooled slowly to room temperature. The mixture is chilled. The crystals which separate are collected. The crude product is recrystallized from tetrahydrofuran to yield 3.04 gm (50%) of the title compound, having a melting point of 217°-218° C.

1. temperatureis refluxed for 9 hrs
2. filtrationThe hot solution is filtered
3. temperatureThe mixture is chilled
4. customThe crystals which separate
5. customare collected
6. customThe crude product is recrystallized from tetrahydrofuran