2-Quinolinecarboxaldehyde → 3-Nitrobenzoic acid (2-quinolinylmethylene)hydrazide

Participants

Reaction Steps

A mixture of 3.00 gm (0.019 mole) of 2-quinolinecarboxaldehyde, 3.44 gm (0.019 mole) of m-nitrobenzhydrazide and 100 ml of ethanol is refluxed for 9 hrs. The hot solution is filtered and cooled slowly to room temperature. The mixture is chilled. The crystals which separate are collected. The crude product is recrystallized from tetrahydrofuran to yield 3.04 gm (50%) of the title compound, having a melting point of 217°-218° C.

Provenance & Evidence