HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Amino-2-propanol → 3-(Benzylamino)propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Amino-2-propanol | HCID 4 | — |
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | 2-Chlorobenzaldehyde | HCID 6996 | — |
| Reactant | 3-Amino-1-propanol | HCID 9086 | — |
| Product | 3-(Benzylamino)propanol | HCID 78448 | — |
| Product | 1-(4-benzyl-1,4-oxazepan-2-yl)methanamine(SALTDATA: FREE) | HCID 10421023 | — |
Reaction Steps
3-Benzylaminopropanol is prepared in substantially the same manner as in Reference Example 72, using 3-aminopropanol and benzaldehyde, respectively, in place of 2-amino-1-methylethanol and 2-chlorobenzaldehyde in Reference Example 72. This product is converted to the oily title compound in substantially the same manner as in Reference Examples 73 to 76.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04870074 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-a3efbb5e45704e25b79f3ef4b4c0bb8f |
| Source note | uspto-grants-1989_09 |