Acetyl chloride → Bis(1-methylethyl) B-phenylboronate

HRID 1608316Notes

Reaction equation

HRID 1608316 reaction equation
[C:1]1([Li])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:8]([O:11][B:12](OC(C)C)[O:13][CH:14]([CH3:16])[CH3:15])([CH3:10])[CH3:9].C(Cl)(=O)C>>[C:1]1([B:12]([O:13][CH:14]([CH3:16])[CH3:15])[O:11][CH:8]([CH3:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 21531Triisopropyl borateHCID 178506676HCID 178506676, compound

Product 1

HCID 569210Bis(1-methylethyl) B-phenylboronate

Procedure

Following the procedure of Example 9, phenyllithium (17 mL, 30.6 mmol) and triisopropoxyborane (5.6 g, 30 mmol) were reacted, and the reaction quenched with acetyl chloride (2.1 mL, 30 mmol) to yield after distillation 5.2 g (25.2 mmol, 84%).

Workup

  1. customwere reacted
  2. customto yield
  3. distillationafter distillation 5.2 g (25.2 mmol, 84%)

Sources & evidence

ORD record
ord-33bcb0c2a2314db6bd624f30edeea527
Source dataset
uspto-grants-1989_09
Patent number
US04870177

Reaction notes

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