HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-6,7,8-trifluoro-, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 178472019 | HCID 178472019 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-6,7,8-trifluoro-, ethyl ester | HCID 2733972 | — |
Reaction Steps
7.7 g of the compound from Example 6 and 2.9 g of K2CO3 are heated at 140°-5° C. for 4 hours in 36 ml of DMF. The mixture is subsequently poured onto ice and acidified, and the precipitated solid is separated off and dried. Yield: 4.5 g, melting point: 279°-82° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04870182 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-8053176ab59749eda6ce744e959dc7da |
| Source note | uspto-grants-1989_09 |