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HRID 1608358作成日:2026年10月25日

HCID 178472080、化合物 → Ethyl 7-chloro-6-fluoro-4-hydroxy-8-nitro-3-quinolinecarboxylate

https://huagongshe.com/reaction/1608358

反応式

関与物質

役割名称HCID仕込み量
反応物HCID 178472080HCID 178472080—
溶媒1,4-DioxaneHCID 31275—
生成物Ethyl 7-chloro-6-fluoro-4-hydroxy-8-nitro-3-quinolinecarboxylateHCID 178469671—

反応手順

7.0 g of the product from Example 8 are initially introduced into 100 ml of dioxane. 4.7 g of potassium tert.-butylate are added to this in portions. The mixture is stirred for 24 hours at room temperature, poured onto ice, and neutralized. The precipitated solid is isolated and dried. Yield: 5.3 g, melting point: 224°-7° (decomposes)

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04870182
出典データセットuspto-grants-1989_09
ORD IDord-6a27ac59c602434099df9c2ef2456602
出典メモuspto-grants-1989_09