化工社化工社 化学情報印刷レポート · 研究参考用
HCID 178472080、化合物 → Ethyl 7-chloro-6-fluoro-4-hydroxy-8-nitro-3-quinolinecarboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | HCID 178472080 | HCID 178472080 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | Ethyl 7-chloro-6-fluoro-4-hydroxy-8-nitro-3-quinolinecarboxylate | HCID 178469671 | — |
反応手順
7.0 g of the product from Example 8 are initially introduced into 100 ml of dioxane. 4.7 g of potassium tert.-butylate are added to this in portions. The mixture is stirred for 24 hours at room temperature, poured onto ice, and neutralized. The precipitated solid is isolated and dried. Yield: 5.3 g, melting point: 224°-7° (decomposes)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04870182 |
| 出典データセット | uspto-grants-1989_09 |
| ORD ID | ord-6a27ac59c602434099df9c2ef2456602 |
| 出典メモ | uspto-grants-1989_09 |