Acetyl chloride → Bis(1-methylethyl) B-phenylboronate

HRID 1608378Notes

Reaction equation

HRID 1608378 reaction equation
[C:1]1([Li])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:8]([O:11][B:12](OC(C)C)[O:13][CH:14]([CH3:16])[CH3:15])([CH3:10])[CH3:9].C(Cl)(=O)C>>[C:1]1([B:12]([O:13][CH:14]([CH3:16])[CH3:15])[O:11][CH:8]([CH3:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 21531Triisopropyl borateHCID 178506676HCID 178506676, compound

Product 1

HCID 569210Bis(1-methylethyl) B-phenylboronate

Procedure

Following the procedure of Example 9, phenyllithium (17 mL, 30.6 mmol) and triisopropoxyborane (5.6 g, 30 mmol) were reacted, and the reaction quenched with acetyl chloride (2.1 mL, 30 mmol) to yield after distillation 5.2 g (25.2 mmol, 84%).

Workup

  1. customwere reacted
  2. customto yield
  3. distillationafter distillation 5.2 g (25.2 mmol, 84%)

Sources & evidence

ORD record
ord-1f96f885a22640ff97fb3f49121a6209
Source dataset
uspto-grants-1989_09
Patent number
US04870212

Reaction notes

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