Benzene → HCID 54447535, compound

HRID 1608402Notes

Reaction equation

HRID 1608402 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)=[C:9]([N:12]2[C:16]([CH3:17])=[N:15][N:14]=[N:13]2)C=O)=[CH:4][CH:3]=1.C1(P(=[CH:44][CH:45]=[O:46])(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[CH:47]1C=CC=CC=1>>[F:24][C:21]1[CH:22]=[CH:23][C:18]([C:8]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)=[C:9]([N:12]2[C:16]([CH3:17])=[N:15][N:14]=[N:13]2)[CH:47]=[CH:44][CH:45]=[O:46])=[CH:19][CH:20]=1

Participants

4

Reactant 3

HCID 241BenzeneHCID 75051(Triphenylphosphoranylidene)acetaldehydeHCID 14877943HCID 14877943, compound

Product 1

HCID 54447535HCID 54447535, compoundYield 85%

Procedure

Following the general procedure of Example 7, 3.8 g (11.6 mmoles) of 3,3-bis(4-fluorophenyl)-2-(5-methyl-1H-tetrazol-1-yl)-2-propenal in 200 mL of dry benzene was treated with 3.8 g (12.5 mmoles) of triphenylphosphoranylidene acetaldehyde to produce 3.5 g (85%) of the title compound; m.p.=72°-78° C. (foam).

Sources & evidence

ORD record
ord-8fe786664aaf415a9d297089982edf2f
Source dataset
uspto-grants-1989_09
Patent number
US04870187

Reaction notes

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