Chloroform → HCID 54395344, compound

HRID 1608431Notes

Reaction equation

HRID 1608431 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[OH:12][CH2:13][CH2:14][CH:15]1[C:24]2[C:19](=[CH:20][C:21]([CH2:26][CH2:27][CH2:28][S:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:22][C:23]=2[OH:25])[N:18]([CH3:34])[CH:17]([CH3:35])[CH2:16]1.C(Cl)(Cl)Cl>C(O)(=O)C>[OH:12][CH2:13][CH2:14][CH:15]1[C:24]2[C:19](=[CH:20][C:21]([CH2:26][CH2:27][CH2:28][S:29]([CH2:30][CH2:31][CH2:32][CH3:33])=[O:9])=[CH:22][C:23]=2[OH:25])[N:18]([CH3:34])[CH:17]([CH3:35])[CH2:16]1

Participants

5

Reactant 3

HCID 6212ChloroformHCID 70297m-Chloroperbenzoic acidHCID 19848791HCID 19848791, compound

Product 1

HCID 54395344HCID 54395344, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Equimolar amounts of m-chloroperbenzoic acid and dl-4-(2-hydroxyethyl)-5-hydroxy-1,2-dimethyl-7-(4-thiaoctyl)-1,2,3,4-tetrahydroquinoline are added to a mixture of chloroform and acetic acid (2:1 v/v) and the mixture stirred at room temperature for one hour. The mixture is washed with water, the organic phase dried (MgSO4) and evaporated to dryness at reduced pressure to afford the title compound.

Workup

  1. washThe mixture is washed with water
  2. dry with materialthe organic phase dried (MgSO4)
  3. customevaporated to dryness at reduced pressure

Sources & evidence

ORD record
ord-712e345af3b045638f3fe348c61b9585
Source dataset
uspto-grants-1989_09
Patent number
US04870084

Reaction notes

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