HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-[2-(Methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine → 5-[2-(Methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine.hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-[2-(Methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine | HCID 15229363 | — |
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-[2-(Methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine.hydrochloride | HCID 20086655 | 89.3% |
Reaction Steps
A suspension of 5-[2-(methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine (543 g, 2 mmoles) in methanol (20 ml) was treated with hydrogen chloride-methanol. After the solvent was distilled off, the residue was crystallized from chloroform ether. Then, the crystals thus obtained were washed with ether and dried to obtain 550 mg of the desired product (89.3%, colorless crystals).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05395839 |
| Source dataset | uspto-grants-1995_03 |
| ORD ID | ord-bf831ec700804557a5bda0828d3e5c07 |
| Source note | uspto-grants-1995_03 |