Hydrochloric Acid → HCID 67803491, compound

Participants

Reaction Steps

To a solution of 3.6 mg of methoxymethyl (4S)-5-(2-cyanoethoxy-carbonyl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3-carboxylate in 0.25 ml of dioxane was added 0.1 ml of 1N aqueous sodium hydroxide solution. The mixture was stirred at room temperature for 1 hour. The reaction mixture was diluted with 5 ml of ethyl acetate, to which were added water and 0.1 ml of 1N aqueous hydrochloric acid. The resulting mixture was dried over anhydrous Glauber's salt (sodium sulfate), followed by distilling off the solvent under reduced pressure to obtain 2.6 mg of the objective compound.

Provenance & Evidence