Dimethyl Sulfoxide → 4-benzyloxy-3-[(4-(N-methyl-N-(1-ethoxycarbonylcyclopent-1-yl)amino)-6-(3-(1-methylimidazolin-2-yl)phenoxy)-3,5-difluoropyridin-2-yl)oxy]benzonitrile
Reaction equation
[C:52](=[O:53])([O-:54])[O-:55].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:17][c:18]2[n:19][c:20]([F:38])[c:21]([F:37])[c:22]([N:25]([C:26]3([C:31](=[O:32])[O:33][CH2:34][CH3:35])[CH2:27][CH2:28][CH2:29][CH2:30]3)[CH3:36])[c:23]2[F:24])[cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16]1.[CH3:39][N:40]1[C:41]([c:45]2[cH:46][c:47]([OH:51])[cH:48][cH:49][cH:50]2)=[N:42][CH2:43][CH2:44]1.[CH3:59][S:60]([CH3:61])=[O:62].[CH3:63][CH2:64][O:65][C:66](=[O:67])[CH3:68].[Cs+:56].[Cs+:57].[OH2:58]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:17][c:18]2[n:19][c:20]([O:51][c:47]3[cH:46][c:45]([C:41]4=[N:42][CH2:43][CH2:44][N:40]4[CH3:39])[cH:50][cH:49][cH:48]3)[c:21]([F:37])[c:22]([N:25]([C:26]3([C:31](=[O:32])[O:33][CH2:34][CH3:35])[CH2:27][CH2:28][CH2:29][CH2:30]3)[CH3:36])[c:23]2[F:24])[cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5db07b8de10242f2b59221b3cc82d218
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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