HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18326933, compound → HCID 53835936, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18326933 | HCID 18326933 | — |
| Reactant | HCID 18424405 | HCID 18424405 | — |
| Reactant | t-butyl p-[(R)-2-(p-cyanobenzamido)-3-hydroxypropyl]phenoxyacetate | HCID 53905723 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | HCID 53835936 | HCID 53835936 | — |
Reaction Steps
3.14 g of t-butyl p-[(R)-2-(p-cyanobenzamido)-3-hydroxypropyl]phenoxyacetate were successively reacted with H2S/pyridine, CH3I/acetone and NH4OAc/methanol as described in Example 1. After chromatography on silica gel with water/methanol (100:0 1:1), 1.2 g of t-butyl p-[(R)-2-(p-amidinobenzamido)-3-hydroxypropyl]phenoxyacetate were obtained in the form of a white foam. MS: 428 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05399585 |
| Source dataset | uspto-grants-1995_03 |
| ORD ID | ord-03982210281d44bda5b415fd11643800 |
| Source note | uspto-grants-1995_03 |