Hydrazine hydrate (1:1) → HCID 20083750, compound
Reaction equation
[CH2:1]([O:3][NH:4][C:5](=[O:10])[C:6](OC)=[O:7])[CH3:2].O.[NH2:12][NH2:13]>C(O)C>[CH2:1]([O:3][NH:4][C:5](=[O:10])[C:6]([NH:12][NH2:13])=[O:7])[CH3:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 65 °C
Procedure
A solution of 234 g (1.59 mol) of methyl (ethoxyamino)-oxoacetate in 450 ml of ethanol was added to a solution of 92.8 g (1.855 mol) of hydrazine hydrate in 300 ml of ethanol and the mixture was stirred for 2 hours at 65° C. The mixture was cooled to +10° C., the precipitate was suction filtered, washed with a small amount of cold ethanol, and dried. There was obtained 150 g (64.2% of theory) of 1-(ethoxyamino)-2-(hydrazino)-ethane-1,2-dione as white crystals of m.p. 182° C.
Workup
- temperatureThe mixture was cooled to +10° C.
- filtrationfiltered
- washwashed with a small amount of cold ethanol
- customdried
Sources & evidence
- ORD record
- ord-47f2ff8efb1e4c58b783dba74785d0a9
- Source dataset
- uspto-grants-1995_03
- Patent number
- US05399589
Reaction notes
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