Hydrochloric Acid → HCID 178428935, compound

Participants

Reaction Steps

150 mg of the compound obtained in Example 40 was dissolved in 2 ml of 1N NaOH. The solution was stirred at 60°-70° C. for 24 hours, and then cooled. The pH of the reaction mixture was adjusted to 3 with 1N HCl. The precipitate obtained was collected by filtration, washed with water, and then dried to give 84 mg of a colorless powder of the title compound (yield: 60%).

Provenance & Evidence