Acetic Anhydride → HCID 178474375, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 100 mg of the compound obtained in Example 69 placed in 2 ml of pyridine was added 1 ml of acetic anhydride, followed by stirring at 60° C. for three hours. After the reaction was completed, the reaction mixture was concentrated under reduced pressure. The residue was purified by a silica gel column chromatography (8 g, chloroform:methanol=2:1), whereby 95 mg of a colorless powder of the title compound was obtained (yield: 86%).

Provenance & Evidence