Potassium Carbonate → HCID 20084222, compound

HRID 1609229Notes

Reaction equation

HRID 1609229 reaction equation
[CH:1]1([C:6]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.Cl[CH2:17][C:18]1[CH:27]=[CH:26][C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[N:19]=1.C(=O)([O-])[O-].[K+].[K+]>>[CH:1]1([C:6]([C:8]2[CH:13]=[CH:12][C:11]([O:14][CH2:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)=[CH:10][CH:9]=2)=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 30838232-(Chloromethyl)quinoline hydrochlorideHCID 12239542Methanone, cyclopentyl(4-hydroxyphenyl)-

Product 1

HCID 20084222HCID 20084222, compound

Procedure

In analogy to the procedure of Example III, the title compound is prepared from 21.5 g (0.113 mol) of the compound from Example VII, 25 g (0.116 mol) of 2-chloromethylquinoline hydrochloride and 35.15 g (0.254 mol) of potassium carbonate.

Sources & evidence

ORD record
ord-6aaadb69e0a043a9a9b69611f5a6ff88
Source dataset
uspto-grants-1995_03
Patent number
US05399698

Reaction notes

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