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HRID1609239

反应详情

EQUATION

反应方程式

HRID 1609239 的结构方程式

REACTANTS

反应物

2
结构：O=C(Cl)c1ccc(C(F)(F)F)cc1
HCID67607

Benzoyl chloride, 4-(trifluoromethyl)-

C8H4ClF3O

结构：COc1cccc(O)c1C(C)=O
HCID69709

1-(2-Hydroxy-6-methoxyphenyl)ethan-1-one

C9H10O3

PRODUCTS

生成物

1
结构：COc1cccc2oc(-c3ccc(C(F)(F)F)cc3)cc(=O)c12
HCID9973279

未命名化合物

PROCEDURE

实验过程

3 is prepared from 2-hydroxy-6-methoxyacetophenone and 4-trifluoromethylbenzoyl chloride by the procedure of Example 1. The material is purified by flash chromatography (gradient elution using 25% ethyl acetate in hexane, 40% ethyl acetate in hexane, 60% ethyl acetate in hexane; material is loaded on column in methylene chloride), yielding 3 with a melting point of 190°-191° C.

WORKUP

后处理

  1. customThe material is purified by flash chromatography (gradient elution using 25% ethyl acetate in hexane, 40% ethyl acetate in hexane, 60% ethyl acetate in hexane; material is loaded on column in methylene chloride)
  2. customyielding 3 with a melting point of 190°-191° C.