alpha-Hydroxyacetophenone → HCID 776385, compound

HRID 1609242Notes

Reaction equation

HRID 1609242 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].O[CH2:12][C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:14]>>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]1[O:5][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[C:13](=[O:14])[CH:12]=1

Participants

3

Reactant 2

HCID 68490alpha-HydroxyacetophenoneHCID 702762-Methylbenzoyl chloride

Product 1

HCID 776385HCID 776385, compound

Procedure

7 is prepared from 2-methylbenzoyl chloride (8) and 2-hydroxyacetophenone by the procedure of Example 1. The material is purified by vacuum column (eluting with 10% ethyl acetate in hexane), yielding 7 with a melting point of 45.5°-47.5° C.

Workup

  1. customThe material is purified by vacuum column (eluting with 10% ethyl acetate in hexane)
  2. customyielding 7 with a melting point of 45.5°-47.5° C.

Sources & evidence

ORD record
ord-9d226149205e428da9ef06116dc8a5e7
Source dataset
uspto-grants-1995_03
Patent number
US05399584

Reaction notes

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