HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Dimethylaminopyridine | HCID 21885 | — |
Reaction Steps
Compound 23 was dissolved in dichloromethane (c. 3 mg/ml) and was treated with dicyclohexylcarbodiimide (5 equivalents), a catalytic amount of dimethylaminopyridine, and compound 11 to give after chromatography (silica, 10% methanol/dichloromethane) compound 24.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05401378 |
| Source dataset | uspto-grants-1995_03 |
| ORD ID | ord-fdfa2fd778b240ee918336f7fb3265eb |
| Source note | uspto-grants-1995_03 |