Cyclohexylamine → HCID 67780747, compound

HRID 1609444Notes

Reaction equation

HRID 1609444 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([NH:11][S:12]([CH:15]([CH:20]([CH3:22])[CH3:21])[C:16]([O:18][CH3:19])=[O:17])(=[O:14])=[O:13])[N:4]=1.[CH:23]1([NH2:29])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>CCOCC>[CH:23]1([NH2:29])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1.[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([NH:11][S:12]([CH:15]([CH:20]([CH3:22])[CH3:21])[C:16]([O:18][CH3:19])=[O:17])(=[O:14])=[O:13])[N:4]=1

Participants

4

Reactant 2

HCID 7965CyclohexylamineHCID 20081442HCID 20081442, compound

Product 1

HCID 67780747HCID 67780747, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

A solution of the product of Example 1 (1.0 g) in ether (35 ml) was treated dropwise, with stirring and cooling, with cyclohexylamine (0.3 g) in ether (7 ml). The mixture was stirred for one hour and allowed to stand overnight at room temperature. The precipitated salt was filtered off, washed with ether and dried, yielding 1.15 g (88%), mp 158°-160° C.

Workup

  1. stirringThe mixture was stirred for one hour
  2. filtrationThe precipitated salt was filtered off
  3. washwashed with ether
  4. customdried
  5. customyielding 1.15 g (88%), mp 158°-160° C.

Sources & evidence

ORD record
ord-d6daf9277abc490b8669030e7ef49e65
Source dataset
uspto-grants-1995_03
Patent number
US05401710

Reaction notes

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