Bicyclo(2.2.1)heptan-2-one → 1,2,3,4-Tetrahydro-1,4-methanoacridin-9-amine

HRID 1609474Notes

Reaction equation

HRID 1609474 reaction equation
[C:1](#[N:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[CH2:10]1[CH:14]2[CH2:15][C:16](=O)[CH:12]([CH2:13]2)[CH2:11]1>>[CH2:15]1[CH:14]2[C:10]3[C:11]([CH:12]([CH2:13]2)[CH2:16]1)=[N:4][C:3]1[C:2](=[CH:8][CH:7]=[CH:6][CH:5]=1)[C:1]=3[NH2:9]

Participants

3

Reactant 2

HCID 10345Bicyclo(2.2.1)heptan-2-oneHCID 729132-Aminobenzonitrile

Product 1

HCID 143728181,2,3,4-Tetrahydro-1,4-methanoacridin-9-amine

Procedure

Anthranilonitrile (ortho-isomer) is allowed to react with norcamphor to obtain 9-amino- 1,4-methano- 1,2,3,4-tetrahydroacridine (Formula VIa). ##STR8##

Sources & evidence

ORD record
ord-c022a13c3cba4583a966362b0bd7240f
Source dataset
uspto-grants-1995_03
Patent number
US05401749

Reaction notes

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