Hydrochloric Acid → HCID 15239364, compound

HRID 1609491Notes

Reaction equation

HRID 1609491 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]2[CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13][N:12]2[CH3:21])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[ClH:22]>CCOCC>[ClH:22].[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]2[CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13][N:12]2[CH3:21])=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15239361HCID 15239361, compound

Product 1

HCID 15239364HCID 15239364, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In 50 ml of a solution containing 0.75 g of 3-(4-t-butylphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline in ether, hydrogen chloride gas was bubbled for 40 minutes at room temperature under stirring. The generated crystals were collected by filtration and washed with ether to obtain 0.7 g of 3-(4-t-butylphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrogen chloride salt m.p.: decomposed at 243° C.

Workup

  1. customwas bubbled for 40 minutes at room temperature
  2. filtrationThe generated crystals were collected by filtration
  3. washwashed with ether

Sources & evidence

ORD record
ord-827974dcc0ad4bd894762d5434ace884
Source dataset
uspto-grants-1995_03
Patent number
US05401752

Reaction notes

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