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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1609598Generated: October 25, 2026

2,3-dihydro-6-methoxy-2-(3-pyridylmethyl)-1H-isoindole-1-one → 2,3-dihydro-6-hydroxy-2-(3-pyridylmethyl)-1H-isoindole-1-one

https://huagongshe.com/reaction/1609598

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-dihydro-6-methoxy-2-(3-pyridylmethyl)-1H-isoindole-1-oneHCID 20082009—
SolventHydrogen BromideHCID 260—
Product2,3-dihydro-6-hydroxy-2-(3-pyridylmethyl)-1H-isoindole-1-oneHCID 20081999—

Reaction Steps

The titled compound was prepared in the same manner as in Example 10 (1) b) by refluxing 2,3-dihydro-6-methoxy-2-(3-pyridylmethyl)-1H-isoindole-1-one in 47% hydrogen bromide under heating.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05401756
Source datasetuspto-grants-1995_03
ORD IDord-a32ac53f504a4e81ad47c98644cc799a
Source noteuspto-grants-1995_03