4-Chlorophenol → 7-(4-chlorophenoxy)-2-(3-pyridylmethyl)-1 (2H)-phthalazinone

HRID 1609601Notes

Reaction equation

HRID 1609601 reaction equation
Br[C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[N:7][N:8]([CH2:13][C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[C:9]2=[O:12])=[CH:4][CH:3]=1.[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=1>>[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([O:27][C:2]2[CH:11]=[C:10]3[C:5]([CH:6]=[N:7][N:8]([CH2:13][C:14]4[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=4)[C:9]3=[O:12])=[CH:4][CH:3]=2)=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 46844-ChlorophenolHCID 544303767-Bromo-2-pyridin-3-ylmethyl-2H-phthalazin-1-one

Product 1

HCID 152304797-(4-chlorophenoxy)-2-(3-pyridylmethyl)-1 (2H)-phthalazinone

Procedure

The titled compound was prepared from 7-bromo-2-(3-pyridylmethyl)-1 (2H)-phthalazinone and 4-chlorophenol in the same manner as in Example 1 (1) c).

Sources & evidence

ORD record
ord-c3f218e626a74dd5b538b5c9afa03f7a
Source dataset
uspto-grants-1995_03
Patent number
US05401756

Reaction notes

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