Zinc acetate (USP) → HCID 178511812, compound

Participants

Reaction Steps

L-histidine (2.00 g, 12.8 mmol) was added to an MeOH solution of NaOMe (prepared with Na: 0.30 g, MeOH: 50 ml) at 0° C. and stirred. An MeOH solution (30 ml) of zinc acetate dihydrate (1.41 g) was then slowly dropwise added thereto at room temperature. After stirring for 3 hours, the precipitated crystal (in suspension) was recovered by filtration, washed with water, air dried, and then concentrated under a reduced pressure (5 mmHg, 80° C.).

Provenance & Evidence