Hydrochloric Acid → HCID 19046556, compound

HRID 1609622Notes

Reaction equation

HRID 1609622 reaction equation
[CH3:1][N:2]([CH3:21])[CH2:3][CH2:4][CH:5]([C:9]1[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=1)[C:6]([NH2:8])=[O:7].[ClH:22]>C(O)C>[ClH:22].[CH3:21][N:2]([CH3:1])[CH2:3][CH2:4][CH:5]([C:9]1[CH:10]=[C:11]([O:19][CH3:20])[C:12]([O:17][CH3:18])=[C:13]([O:15][CH3:16])[CH:14]=1)[C:6]([NH2:8])=[O:7]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15233446HCID 15233446, compound

Product 1

HCID 19046556HCID 19046556, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

In 30 ml of ethanol was dissolved 10.8 g of 4-dimethylamino-2-(3,4,5-trimethoxyphenyl)butyramide, followed by addition of a mixture of concentrated hydrochloric acid (3 ml) and ethanol (27 ml). The mixture was stirred at a room temperature for 2 hours. The resulting precipitate was recovered by filtration and dried under reduced pressure to provide 12.2 g of 4-dimethylamino-2-(3,4,5-trimethoxyphenyl)butyramide hydrochloride.

Workup

  1. filtrationThe resulting precipitate was recovered by filtration
  2. customdried under reduced pressure

Sources & evidence

ORD record
ord-73c04d364c0a4f6cb9c70070f3fbce05
Source dataset
uspto-grants-1995_03
Patent number
US05401775

Reaction notes

Loading…