(+-)-2-Butanol → Sec-Butyl Propanoyloxymethyl Carbonate

HRID 1609751Notes

Reaction equation

HRID 1609751 reaction equation
[CH3:1][CH:2]([OH:5])[CH2:3][CH3:4].[C:6](Cl)(=[O:14])[O:7][CH2:8][O:9][C:10](=[O:13])[CH2:11][CH3:12]>>[C:6](=[O:14])([O:7][CH2:8][O:9][C:10](=[O:13])[CH2:11][CH3:12])[O:5][CH:2]([CH2:3][CH3:4])[CH3:1]

Participants

3

Reactant 2

HCID 6568(+-)-2-ButanolHCID 14800977Propanoyloxymethyl Carbonochloridate

Product 1

HCID 20082466Sec-Butyl Propanoyloxymethyl Carbonate

Procedure

A mixture of 2-butanol (0.092 mL, 1 mmol), 7c (0.17 g, 1 mmol), and powdered molecular sieve (0.15 g, 4Å) in alcohol-free CHCl3 (2 mL) is refluxed for 18 h. Following filtration through filter-aid and evaporation 0.2 g (98%) of the title compound is obtained.

Workup

  1. temperatureis refluxed for 18 h
  2. filtrationfiltration
  3. filtrationthrough filter-aid
  4. customevaporation 0.2 g (98%) of the title compound
  5. customis obtained

Sources & evidence

ORD record
ord-c381f5bef7a84f6c953e96cd013b9ce5
Source dataset
uspto-grants-1995_03
Patent number
US05401868

Reaction notes

Loading…