反应详情

To a solution of 6-isopropyl-1,5dimethoxy-cyclohexa-1,4-diene (7 g) in methanol (50 mL) was added 2.5% hydrochloric acid (10 mL) drop wise at 0° C. The reaction mixture was stirred for 45 minutes, then diluted with ice-cold water (30 mL). The product was extracted with ether (3×70 mL). The combined organic extracts were washed with brine and dried over anhydrous sodium sulfate. Removal of the solvent in vacuo yielded the title compound as a light yellow oil (6 g, 93%).

1. extractionThe product was extracted with ether (3×70 mL)
2. washThe combined organic extracts were washed with brine
3. dry with materialdried over anhydrous sodium sulfate
4. customRemoval of the solvent in vacuo