HCID 23590018, compound → HCID 23590015, compound

HRID 1609929Notes

Reaction equation

HRID 1609929 reaction equation
[CH2:1]([O:3][C:4](=[O:38])[C:5]([CH3:37])([O:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][CH2:16][C:17]2[N:18]=[C:19]([C:23]3[CH:28]=[CH:27][C:26]([C:29]#[C:30]C4C=CC=CC=4)=[CH:25][CH:24]=3)[O:20][C:21]=2[CH3:22])=[CH:10][CH:9]=1)[CH3:6])[CH3:2]>CCOC(C)=O>[CH2:1]([O:3][C:4](=[O:38])[C:5]([O:7][C:8]1[CH:9]=[CH:10][C:11]([O:14][CH2:15][CH2:16][C:17]2[N:18]=[C:19]([C:23]3[CH:28]=[CH:27][C:26]([C:29]#[CH:30])=[CH:25][CH:24]=3)[O:20][C:21]=2[CH3:22])=[CH:12][CH:13]=1)([CH3:6])[CH3:37])[CH3:2]

Participants

3

Reactant 1

HCID 23590018HCID 23590018, compound

Product 1

HCID 23590015HCID 23590015, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

2-Methyl-2-(4-{2-[5-methyl-2-(4-phenylethynylphenyl)-oxazol-4-yl]ethoxy}-phenoxy)propionic acid ethyl ester Rf=0.38 in 1:4 EtOAc:hexanes; 1H NMR (400 MHz, CDCl3) δ 7.93 (d, 2H), 7.56 (d, 2H) 7.48, (m, 2H), 7.33-7.32 (m, 3H) 6.81-6.74 (m, 4H), 4.21-4.15 (m, 4H), 2.93 (t, 2H), 2.34 (s, 3H), 1.53 (s, 6H), 1.24 (t, 3H); MS (EI) 532.2 (M+Na)+, 510.2 (M+H)+.

Sources & evidence

ORD record
ord-767ada88694c4d6a8e936f0dc9417f24
Source dataset
uspto-grants-2006_01
Patent number
US06982278B2

Reaction notes

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