Formaldehyde → N-Methyl-N-pentylpentan-1-amine

HRID 1610049Notes

Reaction equation

HRID 1610049 reaction equation
[CH2:1]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH2:2][CH2:3][CH2:4][CH3:5].[CH2:12]=O>>[CH3:12][N:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])[CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

Participants

3

Reactant 2

HCID 712FormaldehydeHCID 16316Dipentylamine

Product 1

HCID 186925N-Methyl-N-pentylpentan-1-amineYield 96%

Procedure

In a similar manner to Example 1, 314.4 g (2.0 mol) of diamylamine (technical mixture of 18.3% by weight of diisopentylamine, 61.0% by weight of di-n/i-pentylamine and 19.2% by weight of di-n-pentylamine, remainder: 1.5% by weight) and 330.2 g (3.2 mol) of formaldehyde (29.1%) are reacted in a 1 l autoclave; a maximum pressure of 2.5 MPa is established at a temperature of 120° C. After the crude amine (aqueous and organic phase) has been degassed at a maximum temperature of 102° C., the water is removed on a water separator. The remaining organic phase is subsequently distilled. 329.1 g of N-methyldiamylamine having a purity of 91.8% are isolated, corresponding to a yield of 88.3% of theory.

Workup

  1. customis established at a temperature of 120° C
  2. customAfter the crude amine (aqueous and organic phase) has been degassed at a maximum temperature of 102° C.
  3. customthe water is removed on a water separator
  4. distillationThe remaining organic phase is subsequently distilled

Sources & evidence

ORD record
ord-fbe60fc29ceb432a9483d4d33cc08bcb
Source dataset
uspto-grants-2006_01
Patent number
US06982352B2

Reaction notes

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