Hydrazine hydrate (1:1) → HCID 22260785, compound

HRID 1610152Notes

Reaction equation

HRID 1610152 reaction equation
[S:1]1[C:5]([C:6]([C:8]2[CH:13]=[C:12]([Br:14])[C:11]([F:15])=[CH:10][C:9]=2F)=O)=[CH:4][C:3]2[CH:17]=[CH:18][CH:19]=[CH:20][C:2]1=2.O.[NH2:22][NH2:23]>>[S:1]1[C:5]([C:6]2[C:8]3[C:9](=[CH:10][C:11]([F:15])=[C:12]([Br:14])[CH:13]=3)[NH:23][N:22]=2)=[CH:4][C:3]2[CH:17]=[CH:18][CH:19]=[CH:20][C:2]1=2

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 22260723HCID 22260723, compound

Product 1

HCID 22260785HCID 22260785, compound

Procedure

A total of 5.7 g of benzo[b]thiophen-2-yl-(5-bromo-2,4-difluorophenyl)methanone obtained in Production Example II-16-a was allowed to react with hydrazine monohydrate by the procedure of Production Example II-10-c and thereby yielded 0.6 g of the title compound as a colorless powder.

Sources & evidence

ORD record
ord-d49891fde5ac4026924222856c64f0c4
Source dataset
uspto-grants-2006_01
Patent number
US06982274B2

Reaction notes

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