Benzoyl chloride → HCID 22258244, compound

HRID 1610836Notes

Reaction equation

HRID 1610836 reaction equation
[CH3:1][C:2]1[NH:6][C:5]2[CH2:7][CH2:8][CH2:9][CH:10]([CH3:11])[C:4]=2[N:3]=1.[C:12]([Cl:20])(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(#N)C>[ClH:20].[CH3:11][CH:10]1[C:4]2[N:3]=[C:2]([CH2:1][C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[O:19])[NH:6][C:5]=2[CH2:7][CH2:8][CH2:9]1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 22258232HCID 22258232, compound

Product 1

HCID 22258244HCID 22258244, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The compound is prepared as described in example XVII with 1.00 g (6.66 mmol) 2,4-Dimethyl-4,5,6,7-tetrahydro-1H-benzimidazole (example XI, step 1), 3.09 g (21.97 mmol) of benzoyl chloride and 2.36 g (23.30 mmol) of TEA in 20 ml acetonitrile.

Workup

  1. customThe compound is prepared

Sources & evidence

ORD record
ord-ac8aea67fe11455f8935b573deef973d
Source dataset
uspto-grants-2006_01
Patent number
US06984646B2

Reaction notes

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