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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1610847Generated: November 2, 2026

Propiolic Acid → HCID 22258164, compound

https://huagongshe.com/reaction/1610847

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropiolic AcidHCID 10110—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 178520384HCID 178520384—
ProductHCID 22258164HCID 22258164—

Reaction Steps

The compound is prepared as described in example 6 with 446.0 mg (1.58 mmol) of 2-(4-bromo-1H-imidazol-2-yl)-1-(4-fluorophenyl)ethanone (example XXXII), 172.43 mg (2.36 mmol) of propiolic acid and 459.82 mg (2.84 mmol) of 1-(1H-imidazol-1-ylcarbonyl)-1H-imidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06984646B2
Source datasetuspto-grants-2006_01
ORD IDord-4f660e7566b440789e013ad1c531e61d
Source noteuspto-grants-2006_01