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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1610853Generated: November 2, 2026

Propiolic Acid → HCID 22258272, compound

https://huagongshe.com/reaction/1610853

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropiolic AcidHCID 10110—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 22258258HCID 22258258—
ProductHCID 22258272HCID 22258272—

Reaction Steps

The compounds are prepared as described in example 10 with 200 mg (0.70 mmol) of 2-(5,6-Dimethyl-4,5,6,7-tetrahydro-1H-benzimidazol-2-yl)-1-(4-fluorophenyl)ethanone (example XIV), 73.3 mg (1.05 mmol) of propiolic acid and 204 mg (1.26 mmol) of 1-(1H-imidazol-1-ylcarbonyl)-1H-imidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06984646B2
Source datasetuspto-grants-2006_01
ORD IDord-6e2be6ba9a34476399ee578377b5d8cb
Source noteuspto-grants-2006_01