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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1610855Generated: November 2, 2026

Propiolic Acid → HCID 22258296, compound

https://huagongshe.com/reaction/1610855

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropiolic AcidHCID 10110—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 22258310HCID 22258310—
ProductHCID 22258296HCID 22258296—

Reaction Steps

The compounds are prepared as described in example 10 with 200 mg (0.68 mmol) of 2-(4-Butyl-5-methyl-1H-imidazol-2-yl)-1-(2,4-difluorophenyl)ethanone (example XXI), 72 mg (1.03 mmol) of propiolic acid and 200 mg (1.23 mmol) of 1-(1H-imidazol-1yl-carbonyl)-1H-imidazole. The following compounds are obtained:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06984646B2
Source datasetuspto-grants-2006_01
ORD IDord-4c93bf48195a435d87453fab7df760cf
Source noteuspto-grants-2006_01