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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1610857Generated: November 3, 2026

Propiolic Acid → HCID 22258273, compound

https://huagongshe.com/reaction/1610857

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropiolic AcidHCID 10110—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 178439624HCID 178439624—
ProductHCID 22258273HCID 22258273—

Reaction Steps

The compound is prepared as described in example 10 with 65 mg (0.26 mmol) of 1-(4-fluorophenyl)-2-(4-isopropyl-1H-imidazol-2-yl)ethanone (example XXX), 27.7 mg (0.40 mmol) of propiolic acid and 77 mg (0.48 mmol) of 1-(1H-imidazol-1-yl-carbonyl)-1H-imidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06984646B2
Source datasetuspto-grants-2006_01
ORD IDord-df6a3410db8d4776b0b66e6fc9cc357d
Source noteuspto-grants-2006_01