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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1610859Generated: November 2, 2026

Methyl propiolate → HCID 22258179, compound

https://huagongshe.com/reaction/1610859

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl propiolateHCID 13536—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 22258236HCID 22258236—
ProductHCID 22258179HCID 22258179—

Reaction Steps

The compound is prepared as described in example 20 with 200 mg (0.65 mmol) of 1-(4-fluorophenyl)-2-(4-methyl-4,5,6,7-tetrahydro-1H-benzimidazol-2-yl)ethanone hydrochloride (example XVI), 50 mg (0.93 mmol) of sodium methylate and 54.4 mg (0.65 mmol) methyl propiolate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06984646B2
Source datasetuspto-grants-2006_01
ORD IDord-14a0f8786b90410b88a3732ec195ef6e
Source noteuspto-grants-2006_01