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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1610865Generated: November 1, 2026

Methyl propiolate → HCID 22258220, compound

https://huagongshe.com/reaction/1610865

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl propiolateHCID 13536—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 22258217HCID 22258217—
ProductHCID 22258220HCID 22258220—

Reaction Steps

The compound is prepared as described in example 20 with 200 mg (0.72 mmol) of 1-(3,4-Difluorophenyl)-2-(4,5,6,7-tetrahydro-1H-benzimidazol-2-yl)ethanone (example XXXVII), 78.2 mg (1.45 mmol) of sodium methylate and 60.9 mg (0.72 mmol) methyl propiolate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06984646B2
Source datasetuspto-grants-2006_01
ORD IDord-830dc7a57e434efca1347b0fe68d6215
Source noteuspto-grants-2006_01