Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1610880Generated: November 1, 2026

Methyl propiolate → HCID 22258190, compound

https://huagongshe.com/reaction/1610880

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl propiolateHCID 13536—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 178432801HCID 178432801—
ProductHCID 22258190HCID 22258190—

Reaction Steps

The compound is prepared as described in example 25 with 300 mg (0.91 mmol) of 1-(4-fluorophenyl)-2-(4-methyl-5-phenyl-1H-imidazol-2-yl)ethanone hydrochloride (example LI), 90 mg (1.80 mmol) of sodium methylate and 76 mg (0.91 mmol) methyl propiolate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06984646B2
Source datasetuspto-grants-2006_01
ORD IDord-72db465e63fc4c61862c8054010d4282
Source noteuspto-grants-2006_01