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HRID1610979

反应详情

EQUATION

反应方程式

HRID 1610979 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：Fc1cccc(F)c1/C=C/c1nc(CCl)co1
HCID22259292

4-(Chloromethyl)-2-[(1E)-2-(2,6-difluorophenyl)ethenyl]oxazole

C12H8ClF2NO

结构：CS(=O)(=O)Cc1nccn1CCCCc1ccc(O)cc1
HCID22259297

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)Cc1nccn1CCCCc1ccc(OCc2coc(/C=C/c3c(F)cccc3F)n2)cc1
HCID22259353

未命名化合物

收率 65.5%

PROCEDURE

实验过程

Using 4-(chloromethyl)-2-[(E)-2-(2,6-difluorophenyl)ethenyl]-1,3-oxazole (228 mg), 4-[4-[2-[(methylsulfonyl)methyl]-1H-imidazol-1-yl]butyl]phenol (250 mg). and 65% sodium hydride (32.9 mg), the same reaction as Example 11-(i) was carried out to yield the titled compound (280 mg) as colorless needle crystals.