HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22259359, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-[4-[2-[(methylsulfonyl)methyl]-1H-imidazol-1-yl]butyl]phenol | HCID 22259297 | — |
| Reactant | HCID 22259331 | HCID 22259331 | — |
| Product | HCID 22259359 | HCID 22259359 | 62.9% |
Reaction Steps
Using 2-[(E)-2-(4-chloro-3-fluorophenyl)ethenyl]-4-(chloromethyl)-1,3-oxazole (291 mg), 4-[4-[2-[(methylsulfonyl)methyl]-1H-imidazol-1-yl]butyl]phenol (300 mg) and 65% sodium hydride (39.5 mg), the same reaction as Example 11-(i) was carried out to yield the titled compound (333 mg) as colorless needle crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06984653B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-62e87ed2d48748cfbdaad8be86f87b94 |
| Source note | uspto-grants-2006_01 |