Water → HCID 22259535, compound

HRID 1611005Notes

Reaction equation

HRID 1611005 reaction equation
O.[C:2]1([CH3:8])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[O-]S([O-])(=O)=O.[Cu+2]>[CH2:8]=[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]2[C:3]1=[CH:6][CH:7]=[C:2]2[C:3]1[CH2:8][C:2]2[C:7]([CH:4]=1)=[CH:6][CH:5]=[CH:4][CH:3]=2

Participants

4

Reactant 2

HCID 962WaterHCID 1140Toluene

Product 1

HCID 22259535HCID 22259535, compound

Reagents, catalysts & solvents 1

HCID 24462Copper SulfateCatalyst

Procedure

The alcohol is added to the suspension of CuSO4 in toluene. After 90 minutes at 110° C. the mixture is poured into water and extracted with ethyl ether. After washing the organic extracts to neutrality with water and anhydrifying on Na2SO4, the solvent is evaporated. 1.8 g of 4-methylene(2-indenyl)indene are obtained, after purification on a silica gel column (eluant: hexane/ethyl acetate=99/1).

Workup

  1. extractionextracted with ethyl ether
  2. washAfter washing the organic extracts to neutrality with water and anhydrifying on Na2SO4
  3. customthe solvent is evaporated

Sources & evidence

ORD record
ord-d9cfea34021c4394909a6b834974047b
Source dataset
uspto-grants-2006_01
Patent number
US06984703B1

Reaction notes

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