Methyl iodide → HCID 22258017, compound

HRID 1611021Notes

Reaction equation

HRID 1611021 reaction equation
[C:1]([NH:4][C:5](=[O:27])[N:6]([CH:24]([CH3:26])[CH3:25])[C:7]1[S:8][C:9]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:10][C:11]=1[C:12](OCC)=[O:13])(=O)C.[O-]CC.[Na+].IC>>[CH3:1][N:4]1[C:12](=[O:13])[C:11]2[CH:10]=[C:9]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[S:8][C:7]=2[N:6]([CH:24]([CH3:26])[CH3:25])[C:5]1=[O:27]

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 2723922Sodium ethoxideHCID 22257976HCID 22257976, compound

Product 1

HCID 22258017HCID 22258017, compound

Procedure

Prepared from N′-acetyl-N-(1-methylethyl)-N-[3-ethoxycarbonyl-5-(phenylmethyl)-2-thienyl]urea (700 mg), sodium ethoxide (400 mg) and iodomethane (0.45 ml) following the method of Example 12, step d) to give the title compound.

Sources & evidence

ORD record
ord-5ae13b6b7531437998e444cdae0b80f7
Source dataset
uspto-grants-2006_01
Patent number
US06984644B2

Reaction notes

Loading…