3-Amino-1-propanol → HCID 21947127, compound

HRID 1611234Notes

Reaction equation

HRID 1611234 reaction equation
[CH3:1][C:2]1[CH2:7][CH2:6][CH2:5][C:4]([CH3:9])([CH3:8])[C:3]=1[CH2:10][CH2:11][C:12](=[O:14])[CH3:13].S([O-])([O-])(=O)=O.[Na+].[Na+].[NH2:22][CH2:23][CH2:24][CH2:25]O>CO>[CH3:13][C:12]1([CH2:11][CH2:10][C:3]2[C:4]([CH3:8])([CH3:9])[CH2:5][CH2:6][CH2:7][C:2]=2[CH3:1])[NH:22][CH2:23][CH2:24][CH2:25][O:14]1

Participants

5

Reactant 3

HCID 90863-Amino-1-propanolHCID 24436Sodium SulfateHCID 519382Dihydro-beta-ionone

Product 1

HCID 21947127HCID 21947127, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a 0° C. stirred solution of 4-(2,6,6-trimethyl-cyclohex-1-enyl)-butan-2-one (25.2 g, 0.13 mol) and sodium sulfate (20 g) in 80 mL of methanol is added 3-amino-1-propanol (10 g, 0.13 mol). The reaction is allowed to warm to room temperature. After stirring for 24 h the mixture is cooled to 0° C. and the solids are removed via vacuum filtration through Celite. Evaporation of the solvent gives a clear yellow oil.

Workup

  1. temperatureis cooled to 0° C.
  2. customthe solids are removed via vacuum filtration through Celite
  3. customEvaporation of the solvent
  4. customgives a clear yellow oil

Sources & evidence

ORD record
ord-8694168963ad4978b060c0bc34e20ef8
Source dataset
uspto-grants-2006_01
Patent number
US06987084B2

Reaction notes

Loading…