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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611266Generated: October 26, 2026

Cyclobutylmethyl 4-methylbenzenesulfonate → 1-(Cyclobutyl)methyl-5-isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutylmethyl 4-methylbenzenesulfonateHCID 13163931—
Reactant6-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dioneHCID 22256582—
Product1-(Cyclobutyl)methyl-5-isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedioneHCID 159577041.3%

Reaction Steps

5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and (cyclobutyl)methyl para-toluenesulfonate were reacted by the same way ith the example 1 to obtain the titled compound (182 mg, yield: 1.3%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-602101b4adea4de7881b5ef8fc77e43d
Source noteuspto-grants-2006_01