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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611290Generated: October 27, 2026

2-(Bromomethyl)benzonitrile → 1-(2-Cyanobenzyl)-5-ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611290

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)benzonitrileHCID 89599—
Reactant5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedioneHCID 10923266—
Product1-(2-Cyanobenzyl)-5-ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedioneHCID 1595772353.5%

Reaction Steps

5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 2-cyanobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (201 mg, yield: 53.5%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-90c7724146ef4b0fb44450a1cfdc8500
Source noteuspto-grants-2006_01