HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)benzonitrile → 1-(2-Cyanobenzyl)-5-isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)benzonitrile | HCID 89599 | — |
| Reactant | 6-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione | HCID 22256582 | — |
| Product | 1-(2-Cyanobenzyl)-5-isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione | HCID 15957726 | 57.5% |
Reaction Steps
5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and 2-cyanobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (231 mg, yield: 57.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06987114B1 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-043088947c934903b1d66708d3f7c715 |
| Source note | uspto-grants-2006_01 |